The second series, The Second Guest is similarly set with 25 stories, except this time the main victim is a woman who has just taken a taxi home from her best friend's wedding ceremony.

Episode 1
Night 1: Haniwa Salaryman
Apr 1, 2000
A woman on her way from her friend's wedding checks in, and gets a glance at what the first guest had become...

Episode 2
Night 2: Gregory
Apr 8, 2000
Gregory brings the Second Guest a rose with touchy-feely issues...

Episode 3
Night 3: Hell's Chef
Apr 15, 2000
Even when smoking's allowed at Gregory House, you're better off not doing it when the chef draws near...

Episode 4
Night 4: Catherine
Apr 22, 2000
The Second Guest overhears a conversation between Gregory and Catherine about her.

Episode 5
Night 5: James
Apr 29, 2000
James makes his debut, with blood-draining results.

Episode 6
Night 6: Lost Doll
May 6, 2000
To make up for his bad behavior the previous night, James gives the Second Guest a present... Lost Doll.

Episode 7
Night 7: Clock Master & My Son
May 13, 2000
The Second Guest has one of Gregory's specialty cocktails.

Episode 8
Night 8: Sleepy Sheep
May 20, 2000
Sleepy Sheep tries to help the Second Guest to sleep.

Episode 9
Night 9: Bonsai Kabuki
May 27, 2000
Fantasy time! The Second Guest has a strange dream with a very strange man.

Episode 10
Night 10: Cactus Gunman
Jun 3, 2000
There are flames in the Second Guest's very near future. Could it be the fire of the Gunman's pistols?

Episode 11
Night 11: Cactus Girl
Jun 10, 2000
Cactus Girl tries to get the Second Guest to date her big brother... by threatening to hang Gregory.

Episode 12
Night 12: Judgement Boy Gold
Jun 17, 2000
The Second Guest watches the Judgement Boys practice their Judgement Game... then gets her heavy heart weighted.

Episode 13
Night 13: Gregory Mama
Jun 24, 2000
The Second Guest has a very scary run-in with the magic of Gregory Mama.

Episode 14
Night 14: Trap Mouse
Jul 1, 2000
James has a little difficulty giving the Second Guest a gift... a transmitter for the mechanical munching Trap Mouse.

Episode 15
Night 15: Hell's Taxi
Jul 8, 2000
The Second Guest's bid for freedom doesn't go so well... mostly because James is hitching a ride with her.

Episode 16
Night 16: Poor Conductor
Jul 15, 2000
Wandering lost in the forest around the hotel, the Second Guess finds a very depressed conductor in the graveyard.

Episode 17
Night 17: Umbaba
Jul 22, 2000
Gregory plans to shake the Second Guest's soul of her body with Umbaba's rhythm, but James's interference sends the blasts swinging wide.

Episode 18
Night 18: Gregory Mama
Jul 29, 2000
Barely escaping from Gregory Mama, Gregory, James, and the Second Guest hurry for their bodies.

Episode 19
Night 19: Gregory
Aug 5, 2000
Gregory and James's souls have switched bodies! Leave it to James to get Gregory in trouble with his mother. Meanwhile, the Second Guest, still bodiless, drifts further.

Episode 20
Night 20: Death
Aug 12, 2000
The soul of the Second Guest gets a helping hand from Death. The only episode to not have Gregory.

Episode 21
Night 21: Mono Eye Wizard
Aug 19, 2000
The Second Guest doesn't have much time before her body is destroyed.

Episode 22
Night 22: TV Fish
Aug 26, 2000
A very angry Second Guest, via TV Fish, evesdrops on a conversation between Gregory and his mother.

Episode 23
Night 23: Neko Zombie
Sep 2, 2000
The imprisoned cat's last stand is at hand. "Let's put an end to this, once and for all!"

Episode 24
Night 24: Neko Zombie
Sep 9, 2000
Gregory House is going down in flames! In order to destroy this world for sure, can the Second Guest make the sacrifice?

Episode 25
Night 25: Gregory
Sep 16, 2000
The air, white with ashy fog. The charred remains of a structure are all that stands. The Second Guest has made her choice; now, only eternity lies ahead. "It's time to greet our next guest!"